Effects of systemic inhibitors of acid‐sensing ion channels 1 (ASIC1) against acute and chronic mechanical allodynia in a rodent model of migraine

BACKGROUND AND PURPOSE: Acid‐sensing ion channels (ASICs) are neuronal proton sensors emerging as potential therapeutic targets in pain of the orofacial region. Amiloride, a non‐specific ASIC blocker, has been shown to exert beneficial effects in animal models of migraine and in patients. We explore...

Full description

Saved in:
Bibliographic Details
Published in:Br J Pharmacol
Main Authors: Verkest, Clément, Piquet, Emilie, Diochot, Sylvie, Dauvois, Mélodie, Lanteri‐Minet, Michel, Lingueglia, Eric, Baron, Anne
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177611/
https://ncbi.nlm.nih.gov/pubmed/30079481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14462
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items