ASIC3, a sensor of acidic and primary inflammatory pain

Acid-sensing ion channels (ASICs) are cationic channels activated by extracellular acidosis that are expressed in both central and peripheral nervous systems. Although peripheral ASICs seem to be natural sensors of acidic pain (e.g., in inflammation, ischaemia, lesions or tumours), a direct demonstr...

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Autors principals: Deval, Emmanuel, Noël, Jacques, Lay, Nadège, Alloui, Abdelkrim, Diochot, Sylvie, Friend, Valérie, Jodar, Martine, Lazdunski, Michel, Lingueglia, Eric
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585165/
https://ncbi.nlm.nih.gov/pubmed/18923424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.213
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