The mechano-activated K(+) channels TRAAK and TREK-1 control both warm and cold perception

The sensation of cold or heat depends on the activation of specific nerve endings in the skin. This involves heat- and cold-sensitive excitatory transient receptor potential (TRP) channels. However, we show here that the mechano-gated and highly temperature-sensitive potassium channels of the TREK/T...

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Detalhes bibliográficos
Main Authors: Noël, Jacques, Zimmermann, Katharina, Busserolles, Jérome, Deval, Emanuel, Alloui, Abdelkrim, Diochot, Sylvie, Guy, Nicolas, Borsotto, Marc, Reeh, Peter, Eschalier, Alain, Lazdunski, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683043/
https://ncbi.nlm.nih.gov/pubmed/19279663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.57
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