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Human ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions
In rodent sensory neurons, acid-sensing ion channel 3 (ASIC3) has recently emerged as a particularly important sensor of nonadaptive pain associated with tissue acidosis. However, little is known about the human ASIC3 channel, which includes three splice variants differing in their C-terminal domain...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3420194/ https://ncbi.nlm.nih.gov/pubmed/22829666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120350109 |
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