Endogenous Neuropeptide Nocistatin Is a Direct Agonist of Acid-Sensing Ion Channels (ASIC1, ASIC2 and ASIC3)

Acid-sensing ion channel (ASIC) channels belong to the family of ligand-gated ion channels known as acid-sensing (proton-gated) ion channels. Only a few activators of ASICs are known. These are exogenous and endogenous molecules that cause a persistent, slowly desensitized current, different from an...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Osmakov, Dmitry I., Koshelev, Sergey G., Ivanov, Igor A., Andreev, Yaroslav A., Kozlov, Sergey A.
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769468/
https://ncbi.nlm.nih.gov/pubmed/31443477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9090401
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