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Structure, function, and pharmacology of acid-sensing ion channels (ASICs): focus on ASIC1a

Acid-sensing ion channels (ASICs) are H(+)-gated Na(+) channels, which are present in most, if not all, neurons. The typical ASIC current is transient and is elicited by a rapid drop in the extracellular pH. In the human genome, four genes for ASICs are present: asic1 – 4. In this review, we will fo...

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Dettagli Bibliografici
Autori principali: Gründer, Stefan, Chen, Xuanmao
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047259/
https://ncbi.nlm.nih.gov/pubmed/21383888
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