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Permeating protons contribute to tachyphylaxis of the acid-sensing ion channel (ASIC) 1a
The homomeric acid-sensing ion channel 1a (ASIC1a) is a H(+)-activated ion channel with important physiological functions and pathophysiological impact in the central nervous system. Here we show that homomeric ASIC1a is distinguished from other ASICs by a reduced response to successive acid stimula...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Blackwell Science Inc
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2151377/ https://ncbi.nlm.nih.gov/pubmed/17204502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.120733 |
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