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Structure, function, and pharmacology of acid-sensing ion channels (ASICs): focus on ASIC1a

Acid-sensing ion channels (ASICs) are H(+)-gated Na(+) channels, which are present in most, if not all, neurons. The typical ASIC current is transient and is elicited by a rapid drop in the extracellular pH. In the human genome, four genes for ASICs are present: asic1 – 4. In this review, we will fo...

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Hlavní autoři: Gründer, Stefan, Chen, Xuanmao
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047259/
https://ncbi.nlm.nih.gov/pubmed/21383888
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