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Glioblastoma cancer stem cell lines express functional acid sensing ion channels ASIC1a and ASIC3

Acidic microenvironment is commonly observed in tumour tissues, including glioblastoma (GBM), the most aggressive and lethal brain tumour in adults. Acid sensing ion channels (ASICs) are neuronal voltage-insensitive sodium channels, which are sensors of extracellular protons. Here we studied and fun...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Tian, Yuemin, Bresenitz, Pia, Reska, Anna, El Moussaoui, Laila, Beier, Christoph Patrick, Gründer, Stefan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651884/
https://ncbi.nlm.nih.gov/pubmed/29057936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13666-9
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