Glioblastoma cancer stem cell lines express functional acid sensing ion channels ASIC1a and ASIC3

Acidic microenvironment is commonly observed in tumour tissues, including glioblastoma (GBM), the most aggressive and lethal brain tumour in adults. Acid sensing ion channels (ASICs) are neuronal voltage-insensitive sodium channels, which are sensors of extracellular protons. Here we studied and fun...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Tian, Yuemin, Bresenitz, Pia, Reska, Anna, El Moussaoui, Laila, Beier, Christoph Patrick, Gründer, Stefan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651884/
https://ncbi.nlm.nih.gov/pubmed/29057936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13666-9
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