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The Interaction between Two Extracellular Linker Regions Controls Sustained Opening of Acid-sensing Ion Channel 1

Activation of acid-sensing ion channels (ASICs) contributes to neuronal death during stroke, to axonal degeneration during neuroinflammation, and to pain during inflammation. Although understanding ASIC gating may help to modulate ASIC activity during these pathologic situations, at present it is po...

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Detalhes bibliográficos
Main Authors: Springauf, Andreas, Bresenitz, Pia, Gründer, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129216/
https://ncbi.nlm.nih.gov/pubmed/21576243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230797
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