Nalaganje...

Potent HIV-1 Protease Inhibitors: Stereoselective Synthesis of a Dipeptide Mimic

The synthesis of a differentially protected dipeptide mimic 10 in enantiomerically pure form is described. The key step involves the epimerization of the C-2 center of the lactone 4, hydrolysis and protection of the resulting hydroxy acid, followed by Curtius rearrangement to introduce the urethane...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Org Chem
Main Authors: Ghosh, Arun K., McKee, Sean P., Thompson, Wayne J., Darke, Paul L., Zugay, Joan C.
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177225/
https://ncbi.nlm.nih.gov/pubmed/30310240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo00057a011
Oznake: Označite
Brez oznak, prvi označite!