An orthotopic glioblastoma animal model suitable for high-throughput screenings

BACKGROUND: Glioblastoma (GBM) is an aggressive form of brain cancer with poor prognosis. Although murine animal models have given valuable insights into the GBM disease biology, they cannot be used in high-throughput screens to identify and profile novel therapies. The only vertebrate model suitabl...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Pudelko, Linda, Edwards, Steven, Balan, Mirela, Nyqvist, Daniel, Al-Saadi, Jonathan, Dittmer, Johannes, Almlöf, Ingrid, Helleday, Thomas, Bräutigam, Lars
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Basic and Translational Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176805/
https://ncbi.nlm.nih.gov/pubmed/29750281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy071
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