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An orthotopic glioblastoma animal model suitable for high-throughput screenings

BACKGROUND: Glioblastoma (GBM) is an aggressive form of brain cancer with poor prognosis. Although murine animal models have given valuable insights into the GBM disease biology, they cannot be used in high-throughput screens to identify and profile novel therapies. The only vertebrate model suitabl...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Pudelko, Linda, Edwards, Steven, Balan, Mirela, Nyqvist, Daniel, Al-Saadi, Jonathan, Dittmer, Johannes, Almlöf, Ingrid, Helleday, Thomas, Bräutigam, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176805/
https://ncbi.nlm.nih.gov/pubmed/29750281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy071
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