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An Orthotopic Glioblastoma Mouse Model Maintaining Brain Parenchymal Physical Constraints and Suitable for Intravital Two-photon Microscopy

Glioblastoma multiforme (GBM) is the most aggressive form of brain tumors with no curative treatments available to date. Murine models of this pathology rely on the injection of a suspension of glioma cells into the brain parenchyma following incision of the dura-mater. Whereas the cells have to be...

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Detalhes bibliográficos
Main Authors: Ricard, Clément, Stanchi, Fabio, Rougon, Geneviève, Debarbieux, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174722/
https://ncbi.nlm.nih.gov/pubmed/24798209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51108
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