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Inhibition of Prolyl Hydroxylases Alters Cell Metabolism and Reverses Pre-Existing Diastolic Dysfunction in Mice
BACKGROUND. Diastolic dysfunction is emerging as a leading cause of heart failure in aging population. Induction of hypoxia tolerance and reprogrammed cell metabolism have emerged as novel therapeutic strategies for the treatment of cardiovascular diseases. METHODS AND RESULTS. In the present study,...
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| Pubblicato in: | Int J Cardiol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6173985/ https://ncbi.nlm.nih.gov/pubmed/30177233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2018.08.065 |
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