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Conditional Knockout of Prolyl Hydroxylase Domain Protein 2 Attenuates High Fat-Diet-Induced Cardiac Dysfunction in Mice

Oxygen sensor prolyl hydroxylases (PHDs) play important roles in the regulation of HIF-α and cell metabolisms. This study was designed to investigate the direct role of PHD2 in high fat-diet (HFD)-induced cardiac dysfunction. In HFD fed mice, PHD2 expression was increased without significant changes...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Zeng, Heng, Chen, Jian-Xiong
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278833/
https://ncbi.nlm.nih.gov/pubmed/25546437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115974
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