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Ablation of endothelial prolyl hydroxylase domain protein‐2 promotes renal vascular remodelling and fibrosis in mice
Accumulating evidence demonstrates that hypoxia‐inducible factor (HIF‐α) hydroxylase system has a critical role in vascular remodelling. Using an endothelial‐specific prolyl hydroxylase domain protein‐2 (PHD2) knockout (PHD2(EC)KO) mouse model, this study investigates the regulatory role of endothel...
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| Izdano u: | J Cell Mol Med |
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| Glavni autori: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5571552/ https://ncbi.nlm.nih.gov/pubmed/28266128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13117 |
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