Ablation of endothelial prolyl hydroxylase domain protein‐2 promotes renal vascular remodelling and fibrosis in mice

Accumulating evidence demonstrates that hypoxia‐inducible factor (HIF‐α) hydroxylase system has a critical role in vascular remodelling. Using an endothelial‐specific prolyl hydroxylase domain protein‐2 (PHD2) knockout (PHD2(EC)KO) mouse model, this study investigates the regulatory role of endothel...

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Bibliografske podrobnosti
izdano v:J Cell Mol Med
Main Authors: Wang, Shuo, Zeng, Heng, Chen, Sean T., Zhou, Liying, Xie, Xue‐Jiao, He, Xiaochen, Tao, Yong‐Kang, Tuo, Qin‐hui, Deng, Changqin, Liao, Duan‐fang, Chen, Jian‐Xiong
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571552/
https://ncbi.nlm.nih.gov/pubmed/28266128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13117
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