Loss of prolyl hydroxylase domain protein 2 in vascular endothelium increases pericyte coverage and promotes pulmonary arterial remodeling

Pulmonary arterial hypertension (PAH) is a leading cause of heart failure. Although pulmonary endothelial dysfunction plays a crucial role in the progression of the PAH, the underlying mechanisms are poorly understood. The HIF-α hydroxylase system is a key player in the regulation of vascular remode...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Wang, Shuo, Zeng, Heng, Xie, Xue-Jiao, Tao, Yong-Kang, He, Xiaochen, Roman, Richard J., Aschner, Judy L., Chen, Jian-Xiong
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper: Pathology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312280/
https://ncbi.nlm.nih.gov/pubmed/27613846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11585
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