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Endothelial prolyl hydroxylase 2 is necessary for angiotensin II-mediated renal fibrosis and injury

Angiotensin II (ANG II) is the key contributor to renal fibrosis and injury. The present study investigated the role of endothelium prolyl hydroxylase 2 (PHD2) in ANG II-mediated renal fibrosis and injury. In vitro, endothelial cells (ECs) were isolated from PHD2(f/f) control [wild-type (WT)] mice o...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Zhao, Yongzhen, Zeng, Heng, Liu, Bo, He, Xiaochen, Chen, Jian-Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473903/
https://ncbi.nlm.nih.gov/pubmed/32715763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00032.2020
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