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High-fat diet induces cardiac remodelling and dysfunction: assessment of the role played by SIRT3 loss

Mitochondrial dysfunction plays an important role in obesity-induced cardiac impairment. SIRT3 is a mitochondrial protein associated with increased human life span and metabolism. This study investigated the functional role of SIRT3 in obesity-induced cardiac dysfunction. Wild-type (WT) and SIRT3 kn...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zeng, Heng, Vaka, Venkata Ramana, He, Xiaochen, Booz, George W, Chen, Jian-Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549035/
https://ncbi.nlm.nih.gov/pubmed/25782072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12556
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