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High-fat diet induces cardiac remodelling and dysfunction: assessment of the role played by SIRT3 loss
Mitochondrial dysfunction plays an important role in obesity-induced cardiac impairment. SIRT3 is a mitochondrial protein associated with increased human life span and metabolism. This study investigated the functional role of SIRT3 in obesity-induced cardiac dysfunction. Wild-type (WT) and SIRT3 kn...
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| Udgivet i: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley & Sons, Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4549035/ https://ncbi.nlm.nih.gov/pubmed/25782072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12556 |
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