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A Sex-Specific Role of Endothelial Sirtuin 3 on Blood Pressure and Diastolic Dysfunction in Female Mice

Background: Heart failure with preserved ejection fraction (HFpEF) is characterized by a diastolic dysfunction and is highly prevalent in aged women. Our study showed that ablation of endothelial Sirtuin 3 (SIRT3) led to diastolic dysfunction in male mice. However, the sex-specific role of endotheli...

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Publicat a:Int J Mol Sci
Autors principals: Zeng, Heng, He, Xiaochen, Chen, Jian-Xiong
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766145/
https://ncbi.nlm.nih.gov/pubmed/33371209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249744
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