Poxviruses evade cytosolic sensing through disruption of an mTORC1-mTORC2 regulatory circuit

Viruses employ elaborate strategies to coopt cellular processes they require to replicate while simultaneously thwarting host antiviral responses. In many instances, how this is accomplished remains poorly understood. Here, we identify a protein, F17 encoded by cytoplasmically-replicating poxviruses...

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Udgivet i:Cell
Main Authors: Meade, Nathan, Furey, Colleen, Li, Hua, Verma, Rita, Chai, Qingqing, Rollins, Madeline G., DiGiuseppe, Stephen, Naghavi, Mojgan H., Walsh, Derek
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172959/
https://ncbi.nlm.nih.gov/pubmed/30078703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.06.053
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