Poxviruses evade cytosolic sensing through disruption of an mTORC1-mTORC2 regulatory circuit

Viruses employ elaborate strategies to coopt cellular processes they require to replicate while simultaneously thwarting host antiviral responses. In many instances, how this is accomplished remains poorly understood. Here, we identify a protein, F17 encoded by cytoplasmically-replicating poxviruses...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Meade, Nathan, Furey, Colleen, Li, Hua, Verma, Rita, Chai, Qingqing, Rollins, Madeline G., DiGiuseppe, Stephen, Naghavi, Mojgan H., Walsh, Derek
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172959/
https://ncbi.nlm.nih.gov/pubmed/30078703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.06.053
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