Interleukin 1 receptor (IL-1R1) activation exacerbates toxin-induced acute kidney injury

Acute kidney injury (AKI) is a leading cause of morbidity and mortality. Drug-induced/toxic AKI can be caused by a number of therapeutic agents. Cisplatin is an effective chemotherapeutic agent whose administration is limited by significant nephrotoxicity. Therapies to prevent cisplatin-induced AKI...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Privratsky, Jamie R., Zhang, Jiandong, Lu, Xiaohan, Rudemiller, Nathan, Wei, Qingqing, Yu, Yen-Rei, Gunn, Michael D., Crowley, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172579/
https://ncbi.nlm.nih.gov/pubmed/29790392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00104.2018
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