Interleukin-1 receptor activation aggravates autosomal dominant polycystic kidney disease by modulating regulated necrosis

Autosomal dominant polycystic kidney disease (ADPKD) is associated with increased chemokines, cytokines, and growth factors in the diseased kidney. We found that both isoforms of IL-1, IL-1α and IL-1β, were upregulated in ADPKD tissues. Here, we used a unique murine ADPKD model with selective deleti...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Am J Physiol Renal Physiol
Huvudupphovsmän: Yang, Bo, Fu, Lili, Privratsky, Jamie R., Lu, Xiaohan, Ren, Jiafa, Mei, Changlin, Crowley, Steven D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732457/
https://ncbi.nlm.nih.gov/pubmed/31141402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00104.2019
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk