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Calpain-6 controls the fate of sarcoma stem cells by promoting autophagy and preventing senescence
Sarcomas are still unsolved therapeutic challenges. Cancer stem cells are believed to contribute to sarcoma development, but lack of specific markers prevents their characterization and targeting. Here, we show that calpain-6 expression is associated with cancer stem cell features. In mouse models o...
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| 出版年: | JCI Insight |
|---|---|
| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6171816/ https://ncbi.nlm.nih.gov/pubmed/30185659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121225 |
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