Functional Annotation of ESR1 Gene Fusions in Estrogen Receptor-Positive Breast Cancer

RNA sequencing (RNA-seq) detects estrogen receptor alpha gene (ESR1) fusion transcripts in estrogen receptor-positive (ER(+)) breast cancer, but their role in disease pathogenesis remains unclear. We examined multiple ESR1 fusions and found that two, both identified in advanced endocrine treatment-r...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Cell Rep
المؤلفون الرئيسيون: Lei, Jonathan T., Shao, Jieya, Zhang, Jin, Iglesia, Michael, Chan, Doug W., Cao, Jin, Anurag, Meenakshi, Singh, Purba, He, Xiaping, Kosaka, Yoshimasa, Matsunuma, Ryoichi, Crowder, Robert, Hoog, Jeremy, Phommaly, Chanpheng, Goncalves, Rodrigo, Ramalho, Susana, Rodrigues Peres, Raquel Mary, Punturi, Nindo, Schmidt, Cheryl, Bartram, Alex, Jou, Eric, Devarakonda, Vaishnavi, Holloway, Kimberly R., Lai, W. Victoria, Hampton, Oliver, Rogers, Anna, Tobias, Ethan, Parikh, Poojan A., Davies, Sherri R., Li, Shunqiang, Ma, Cynthia X., Suman, Vera J., Hunt, Kelly K., Watson, Mark A., Hoadley, Katherine A., Thompson, E. Aubrey, Chen, Xi, Kavuri, Shyam M., Creighton, Chad J., Maher, Christopher A., Perou, Charles M., Haricharan, Svasti, Ellis, Matthew J.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2018
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171747/
https://ncbi.nlm.nih.gov/pubmed/30089255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.07.009
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