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Comprehensive profiling of DNA repair defects in breast cancer identifies a novel class of endocrine therapy resistance drivers
PURPOSE: This study was undertaken to conduct a comprehensive investigation of the role of DNA damage repair (DDR) defects in poor outcome ER+ disease. EXPERIMENTAL DESIGN: Expression and mutational status of DDR genes in ER+ breast tumors were correlated with proliferative response in neoadjuvant a...
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| 出版年: | Clin Cancer Res |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6822623/ https://ncbi.nlm.nih.gov/pubmed/29793947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-3702 |
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