Functional Annotation of ESR1 Gene Fusions in Estrogen Receptor-Positive Breast Cancer

RNA sequencing (RNA-seq) detects estrogen receptor alpha gene (ESR1) fusion transcripts in estrogen receptor-positive (ER(+)) breast cancer, but their role in disease pathogenesis remains unclear. We examined multiple ESR1 fusions and found that two, both identified in advanced endocrine treatment-r...

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Publicat a:Cell Rep
Autors principals: Lei, Jonathan T., Shao, Jieya, Zhang, Jin, Iglesia, Michael, Chan, Doug W., Cao, Jin, Anurag, Meenakshi, Singh, Purba, He, Xiaping, Kosaka, Yoshimasa, Matsunuma, Ryoichi, Crowder, Robert, Hoog, Jeremy, Phommaly, Chanpheng, Goncalves, Rodrigo, Ramalho, Susana, Rodrigues Peres, Raquel Mary, Punturi, Nindo, Schmidt, Cheryl, Bartram, Alex, Jou, Eric, Devarakonda, Vaishnavi, Holloway, Kimberly R., Lai, W. Victoria, Hampton, Oliver, Rogers, Anna, Tobias, Ethan, Parikh, Poojan A., Davies, Sherri R., Li, Shunqiang, Ma, Cynthia X., Suman, Vera J., Hunt, Kelly K., Watson, Mark A., Hoadley, Katherine A., Thompson, E. Aubrey, Chen, Xi, Kavuri, Shyam M., Creighton, Chad J., Maher, Christopher A., Perou, Charles M., Haricharan, Svasti, Ellis, Matthew J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171747/
https://ncbi.nlm.nih.gov/pubmed/30089255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.07.009
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