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DNA copy number profiling using single-cell sequencing

Currently, there is a lack of software for detecting copy number variations and constructing copy number profile for the whole genome from single-cell DNA sequencing data, which are often of low coverage and high technical noises. Here we introduce a new toolkit, SCNV, which features an efficient bi...

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Detalhes bibliográficos
Publicado no:Brief Bioinform
Main Authors: Wang, Xuefeng, Chen, Hao, Zhang, Nancy R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171490/
https://ncbi.nlm.nih.gov/pubmed/28159966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbx004
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