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Allele-specific copy number profiling by next-generation DNA sequencing

The progression and clonal development of tumors often involve amplifications and deletions of genomic DNA. Estimation of allele-specific copy number, which quantifies the number of copies of each allele at each variant loci rather than the total number of chromosome copies, is an important step in...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chen, Hao, Bell, John M., Zavala, Nicolas A., Ji, Hanlee P., Zhang, Nancy R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344483/
https://ncbi.nlm.nih.gov/pubmed/25477383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1252
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