DNA copy number, including telomeres and mitochondria, assayed using next-generation sequencing

BACKGROUND: DNA copy number variations occur within populations and aberrations can cause disease. We sought to develop an improved lab-automatable, cost-efficient, accurate platform to profile DNA copy number. RESULTS: We developed a sequencing-based assay of nuclear, mitochondrial, and telomeric D...

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Detalhes bibliográficos
Main Authors: Castle, John C, Biery, Matthew, Bouzek, Heather, Xie, Tao, Chen, Ronghua, Misura, Kira, Jackson, Stuart, Armour, Christopher D, Johnson, Jason M, Rohl, Carol A, Raymond, Christopher K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867831/
https://ncbi.nlm.nih.gov/pubmed/20398377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-244
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