ALLELE-SPECIFIC COPY NUMBER ESTIMATION BY WHOLE EXOME SEQUENCING

Whole exome sequencing is currently a technology of choice in large-scale cancer genomics studies, where the priority is to identify cancer-associated variants in coding regions. We describe a method for estimating allele-specific copy number using whole exome sequencing data from tumor and matched...

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Bibliografiska uppgifter
I publikationen:Ann Appl Stat
Huvudupphovsmän: Chen, Hao, Jiang, Yuchao, Maxwell, Kara N., Nathanson, Katherine L., Zhang, Nancy
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627665/
https://ncbi.nlm.nih.gov/pubmed/28989557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/17-AOAS1043
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