Global copy number profiling of cancer genomes

Summary: In this article, we introduce a robust and efficient strategy for deriving global and allele-specific copy number alternations (CNA) from cancer whole exome sequencing data based on Log R ratios and B-allele frequencies. Applying the approach to the analysis of over 200 skin cancer samples,...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Wang, Xuefeng, Chen, Mengjie, Yu, Xiaoqing, Pornputtapong, Natapol, Chen, Hao, Zhang, Nancy R., Powers, R. Scott, Krauthammer, Michael
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Applications Notes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907391/
https://ncbi.nlm.nih.gov/pubmed/26576652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv676
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