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MYC-containing amplicons in acute myeloid leukemia: genomic structures, evolution, and transcriptional consequences
Double minutes (dmin), homogeneously staining regions, and ring chromosomes are vehicles of gene amplification in cancer. The underlying mechanism leading to their formation as well as their structure and function in acute myeloid leukemia (AML) remain mysterious. We combined a range of high-resolut...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Leukemia |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group UK
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6170393/ https://ncbi.nlm.nih.gov/pubmed/29467491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0033-0 |
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