The Hidden Genomic and Transcriptomic Plasticity of Giant Marker Chromosomes in Cancer

Genome amplification in the form of rings or giant rod-shaped marker chromosomes (RGMs) is a common genetic alteration in soft tissue tumors. The mitotic stability of these structures is often rescued by perfectly functioning analphoid neocentromeres, which therefore significantly contribute to canc...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Genetics
Κύριοι συγγραφείς: Macchia, Gemma, Severgnini, Marco, Purgato, Stefania, Tolomeo, Doron, Casciaro, Hilen, Cifola, Ingrid, L’Abbate, Alberto, Loverro, Anna, Palumbo, Orazio, Carella, Massimo, Bianchini, Laurence, Perini, Giovanni, De Bellis, Gianluca, Mertens, Fredrik, Rocchi, Mariano, Storlazzi, Clelia Tiziana
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Genetics Society of America 2018
Θέματα:
Investigations
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844343/
https://ncbi.nlm.nih.gov/pubmed/29279323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300552
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