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The Hidden Genomic and Transcriptomic Plasticity of Giant Marker Chromosomes in Cancer
Genome amplification in the form of rings or giant rod-shaped marker chromosomes (RGMs) is a common genetic alteration in soft tissue tumors. The mitotic stability of these structures is often rescued by perfectly functioning analphoid neocentromeres, which therefore significantly contribute to canc...
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| Pubblicato in: | Genetics |
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| Autori principali: | , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Genetics Society of America
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5844343/ https://ncbi.nlm.nih.gov/pubmed/29279323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300552 |
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