Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer

The mechanism for generating double minutes chromosomes (dmin) and homogeneously staining regions (hsr) in cancer is still poorly understood. Through an integrated approach combining next-generation sequencing, single nucleotide polymorphism array, fluorescent in situ hybridization and polymerase ch...

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Detalhes bibliográficos
Main Authors: L'Abbate, Alberto, Macchia, Gemma, D'Addabbo, Pietro, Lonoce, Angelo, Tolomeo, Doron, Trombetta, Domenico, Kok, Klaas, Bartenhagen, Christoph, Whelan, Christopher W., Palumbo, Orazio, Severgnini, Marco, Cifola, Ingrid, Dugas, Martin, Carella, Massimo, De Bellis, Gianluca, Rocchi, Mariano, Carbone, Lucia, Storlazzi, Clelia Tiziana
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132716/
https://ncbi.nlm.nih.gov/pubmed/25034695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku590
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