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Computational design of chemogenetic and optogenetic split proteins

Controlling protein activity with chemogenetics and optogenetics has proven to be powerful for testing hypotheses regarding protein function in rapid biological processes. Controlling proteins by splitting them and then rescuing their activity through inducible reassembly offers great potential to c...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Dagliyan, Onur, Krokhotin, Andrey, Ozkan-Dagliyan, Irem, Deiters, Alexander, Der, Channing J., Hahn, Klaus M., Dokholyan, Nikolay V.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168510/
https://ncbi.nlm.nih.gov/pubmed/30279442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06531-4
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