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Computational design of chemogenetic and optogenetic split proteins

Controlling protein activity with chemogenetics and optogenetics has proven to be powerful for testing hypotheses regarding protein function in rapid biological processes. Controlling proteins by splitting them and then rescuing their activity through inducible reassembly offers great potential to c...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Dagliyan, Onur, Krokhotin, Andrey, Ozkan-Dagliyan, Irem, Deiters, Alexander, Der, Channing J., Hahn, Klaus M., Dokholyan, Nikolay V.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168510/
https://ncbi.nlm.nih.gov/pubmed/30279442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06531-4
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