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Computational design of chemogenetic and optogenetic split proteins

Controlling protein activity with chemogenetics and optogenetics has proven to be powerful for testing hypotheses regarding protein function in rapid biological processes. Controlling proteins by splitting them and then rescuing their activity through inducible reassembly offers great potential to c...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Dagliyan, Onur, Krokhotin, Andrey, Ozkan-Dagliyan, Irem, Deiters, Alexander, Der, Channing J., Hahn, Klaus M., Dokholyan, Nikolay V.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168510/
https://ncbi.nlm.nih.gov/pubmed/30279442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06531-4
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