Carregant...
How Rap and its GEFs control liver physiology and cancer development. C3G alterations in human hepatocarcinoma
Rap proteins regulate liver physiopathology. For example, Rap2B promotes hepatocarcinoma (HCC) growth, while Rap1 might play a dual role. The RapGEF, Epac1, activates Rap upon cAMP binding, regulating metabolism, survival, and liver regeneration. A liver specific Epac2 isoform lacking cAMP-binding d...
Guardat en:
| Publicat a: | Hepat Oncol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Future Medicine Ltd
2018
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6168044/ https://ncbi.nlm.nih.gov/pubmed/30302196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/hep-2017-0026 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|