C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation

BACKGROUND: Megakaryopoiesis allows platelet formation, which is necessary for coagulation, also playing an important role in different pathologies. However, this process remains to be fully characterized. C3G, an activator of Rap1 GTPases, is involved in platelet activation and regulates several di...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Commun Signal
Prif Awduron: Ortiz-Rivero, Sara, Baquero, Cristina, Hernández-Cano, Luis, Roldán-Etcheverry, Juan José, Gutiérrez-Herrero, Sara, Fernández-Infante, Cristina, Martín-Granado, Víctor, Anguita, Eduardo, de Pereda, José María, Porras, Almudena, Guerrero, Carmen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299959/
https://ncbi.nlm.nih.gov/pubmed/30567575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0311-5
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