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C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation

BACKGROUND: Megakaryopoiesis allows platelet formation, which is necessary for coagulation, also playing an important role in different pathologies. However, this process remains to be fully characterized. C3G, an activator of Rap1 GTPases, is involved in platelet activation and regulates several di...

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Bibliografske podrobnosti
izdano v:Cell Commun Signal
Main Authors: Ortiz-Rivero, Sara, Baquero, Cristina, Hernández-Cano, Luis, Roldán-Etcheverry, Juan José, Gutiérrez-Herrero, Sara, Fernández-Infante, Cristina, Martín-Granado, Víctor, Anguita, Eduardo, de Pereda, José María, Porras, Almudena, Guerrero, Carmen
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299959/
https://ncbi.nlm.nih.gov/pubmed/30567575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0311-5
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