(18)F-XTRA PET for Enhanced Imaging of the Extrathalamic α4β2 Nicotinic Acetylcholine Receptor

Reduced density of the α4β2 nicotinic acetylcholine receptor (α4β2-nAChR) in the cortex and hippocampus of the human brain has been reported in aging and patients with neurodegenerative disease. This study assessed the pharmacokinetic behavior of (18)F-(−)-JHU86428 ((18)F-XTRA), a new radiotracer fo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Nucl Med
Prif Awduron: Coughlin, Jennifer M., Slania, Stephanie, Du, Yong, Rosenthal, Hailey B., Lesniak, Wojciech G., Minn, Il, Smith, Gwenn S., Dannals, Robert F., Kuwabara, Hiroto, Wong, Dean F., Wang, Yuchuan, Horti, Andrew G., Pomper, Martin G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society of Nuclear Medicine 2018
Pynciau:
Neurology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167533/
https://ncbi.nlm.nih.gov/pubmed/29496987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.117.205492
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