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23.4 PET-BASED PRECISION NEUROIMAGING OF THE ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR IN PATIENTS WITH RECENT ONSET OF PSYCHOSIS

BACKGROUND: Low availability of the α7 nicotinic acetylcholine receptor (α7-nAChR) in the hippocampus of patients with schizophrenia has been suggested from study of postmortem tissue, and therapies that increase signaling through the α7-nAChR may ameliorate signs and symptoms of psychosis, includin...

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Bibliographic Details
Published in:Schizophr Bull
Main Authors: Coughlin, Jennifer, Du, Yong, Crawford, Jeffrey, Rubin, Leah, Azad, Babak Behnam, Lesniak, Wojciech Lesniak, Horti, Andrew, Schretlen, David, Sawa, Akira, Pomper, Martin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455646/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbz022.094
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