(18)F-XTRA PET for Enhanced Imaging of the Extrathalamic α4β2 Nicotinic Acetylcholine Receptor

Reduced density of the α4β2 nicotinic acetylcholine receptor (α4β2-nAChR) in the cortex and hippocampus of the human brain has been reported in aging and patients with neurodegenerative disease. This study assessed the pharmacokinetic behavior of (18)F-(−)-JHU86428 ((18)F-XTRA), a new radiotracer fo...

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Detaylı Bibliyografya
Yayımlandı:J Nucl Med
Asıl Yazarlar: Coughlin, Jennifer M., Slania, Stephanie, Du, Yong, Rosenthal, Hailey B., Lesniak, Wojciech G., Minn, Il, Smith, Gwenn S., Dannals, Robert F., Kuwabara, Hiroto, Wong, Dean F., Wang, Yuchuan, Horti, Andrew G., Pomper, Martin G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society of Nuclear Medicine 2018
Konular:
Neurology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167533/
https://ncbi.nlm.nih.gov/pubmed/29496987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.117.205492
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