Combined Modulation of Tumor Metabolism by Metformin and Diclofenac in Glioma

Glioblastoma remains a fatal diagnosis. Previous research has shown that metformin, which is an inhibitor of complex I of the respiratory chain, may inhibit some brain tumor initiating cells (BTICs), albeit at dosages that are too high for clinical use. Here, we explored whether a combined treatment...

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Pubblicato in:Int J Mol Sci
Autori principali: Gerthofer, Valeria, Kreutz, Marina, Renner, Kathrin, Jachnik, Birgit, Dettmer, Katja, Oefner, Peter, Riemenschneider, Markus J., Proescholdt, Martin, Vollmann-Zwerenz, Arabel, Hau, Peter, Seliger, Corinna
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163514/
https://ncbi.nlm.nih.gov/pubmed/30200299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092586
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