Metformin inhibits proliferation and migration of glioblastoma cells independently of TGF-β2

To this day, glioblastoma (GBM) remains an incurable brain tumor. Previous research has shown that metformin, an oral anti-diabetic drug, may decrease GBM cell proliferation and migration especially in brain tumor initiating cells (BTICs). As transforming growth factor β 2 (TGF-β(2)) has been report...

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Vydáno v:Cell Cycle
Hlavní autoři: Seliger, Corinna, Meyer, Anne-Louise, Renner, Kathrin, Leidgens, Verena, Moeckel, Sylvia, Jachnik, Birgit, Dettmer, Katja, Tischler, Ulrike, Gerthofer, Valeria, Rauer, Lisa, Uhl, Martin, Proescholdt, Martin, Bogdahn, Ulrich, Riemenschneider, Markus J., Oefner, Peter J., Kreutz, Marina, Vollmann-Zwerenz, Arabel, Hau, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957567/
https://ncbi.nlm.nih.gov/pubmed/27163626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1186316
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