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Ibuprofen and Diclofenac Restrict Migration and Proliferation of Human Glioma Cells by Distinct Molecular Mechanisms

BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAIDs) have been associated with anti-tumorigenic effects in different tumor entities. For glioma, research has generally focused on diclofenac; however data on other NSAIDs, such as ibuprofen, is limited. Therefore, we performed a comprehensive in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Leidgens, Verena, Seliger, Corinna, Jachnik, Birgit, Welz, Tobias, Leukel, Petra, Vollmann-Zwerenz, Arabel, Bogdahn, Ulrich, Kreutz, Marina, Grauer, Oliver M., Hau, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617646/
https://ncbi.nlm.nih.gov/pubmed/26485029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140613
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