Lactate-Modulated Induction of THBS-1 Activates Transforming Growth Factor (TGF)-beta2 and Migration of Glioma Cells In Vitro

BACKGROUND: An important phenomenon observed in glioma metabolism is increased aerobic glycolysis in tumor cells, which is generally referred to as the Warburg effect. Transforming growth factor (TGF)-beta2, which we previously showed to be induced by lactic acid, is a key pathophysiological factor...

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Detalhes bibliográficos
Main Authors: Seliger, Corinna, Leukel, Petra, Moeckel, Sylvia, Jachnik, Birgit, Lottaz, Claudio, Kreutz, Marina, Brawanski, Alexander, Proescholdt, Martin, Bogdahn, Ulrich, Bosserhoff, Anja-Katrin, Vollmann-Zwerenz, Arabel, Hau, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815307/
https://ncbi.nlm.nih.gov/pubmed/24223867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078935
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