Stattic and metformin inhibit brain tumor initiating cells by reducing STAT3-phosphorylation

Glioblastoma (GBM) is the most common and malignant type of primary brain tumor and associated with a devastating prognosis. Signal transducer and activator of transcription number 3 (STAT3) is an important pathogenic factor in GBM and can be specifically inhibited with Stattic. Metformin inhibits G...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Leidgens, Verena, Proske, Judith, Rauer, Lisa, Moeckel, Sylvia, Renner, Kathrin, Bogdahn, Ulrich, Riemenschneider, Markus J., Proescholdt, Martin, Vollmann-Zwerenz, Arabel, Hau, Peter, Seliger, Corinna
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352398/
https://ncbi.nlm.nih.gov/pubmed/28030813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14159
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires